{"id":245,"date":"2023-08-15T17:57:53","date_gmt":"2023-08-15T17:57:53","guid":{"rendered":"https:\/\/mightykidssupplements.net\/vitamin-c-research\/"},"modified":"2025-03-12T16:04:45","modified_gmt":"2025-03-12T16:04:45","slug":"vitamin-c-research","status":"publish","type":"post","link":"https:\/\/mightykids.com\/eu\/vitamin-c-research\/","title":{"rendered":"Our liposomal vitamin C: Research and findings"},"content":{"rendered":"\n

Vitamin C is an essential part of our diet, and is one of the most popular dietary supplements on the market. A bioavailability study that we performed with our liposomal vitamin C formulation had surprising results.<\/p>\n\n\n\n

\"Liposomal<\/figure>\n\n\n\n

Benefits of vitamin C<\/strong><\/h2>\n\n\n\n

Vitamin C (ascorbic acid) plays an important role in various functions of our body such as (1):<\/p>\n\n\n\n

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  1. Maintaining the normal function of the immune system<\/li>\n\n\n\n
  2. Helping with collagen formation for the normal function of blood vessels, bones, cartilage, gums, skin and teeth<\/li>\n\n\n\n
  3. Ensuring the normal functioning of the nervous system<\/li>\n\n\n\n
  4. Reducing tiredness and fatigue and<\/li>\n\n\n\n
  5. Helping to protect cells from oxidative stress<\/li>\n<\/ol>\n\n\n\n

    Limitations of vitamin C<\/strong><\/h3>\n\n\n\n

    As listed above, there are many reasons for taking vitamin C supplements. The most important reason is that the human body is unable to produce this water-soluble vitamin by itself (2). It is essential, therefore, that we consume adequate doses of this essential, water-soluble vitamin through our diet or food supplements.<\/p>\n\n\n\n

    In the market, doses of vitamin C higher than 500 mg\/day are sold as high-dose supplements. The argument for high-dose vitamin C is that the DRV recommendation is for healthy people; however when the body is under stress or when one is ill, higher dosages are required to counter these \u201cattacks\u201d (4,5). Unfortunately, there are also two well-known problems with consuming high-dose ascorbic acid supplements.<\/p>\n\n\n\n

      \n
    1. Taking high dosages of vitamin C orally doesn\u2019t necessarily mean more of it is absorbed. There is a limit to how much the body can absorb. In fact, scientific studies have shown that at single doses above 1000 mg\/day, absorption falls to less than 50% (2). This makes high dosages inefficient.<\/li>\n\n\n\n
    2. The more you take, the more likely you will get unpleasant GI side effects such as nausea and diarrhoea.<\/li>\n<\/ol>\n\n\n\n

      Fortunately, encapsulation of the vitamin into liposomes could help with both of these problems.<\/p>\n\n\n\n

      Liposomes are the solution<\/strong><\/h2>\n\n\n\n

      The GI distress caused by too much vitamin C is due to osmotic forces. This basically means vitamin C attracts water, leading to dehydration. In turn, this can cause various unpleasant side effects (2).<\/p>\n\n\n\n

      By encapsulating vitamin C in liposomes, the exposure to the GI tract is reduced. This reduces its dehydrating side effects (5).<\/p>\n\n\n\n

      Additionally, the absorption of vitamin C in the intestine is carried out through a number of cellular transporters. However, these transporters are easily saturated leading to a limited absorption of vitamin C from supplements (5). Packing vitamin C into liposomes could help it passively cross the intestinal cells and avoid these intestinal transport barriers. Further, due to the re-direction of the liposomes into the lymphatic drainage, the encapsulated vitamin C is directly deposited into the bloodstream. Since the cells of the rest of the body have a different set of transporters for vitamin C, more vitamin C is directly absorbed from the blood (5).<\/p>\n\n\n\n

      Why did we study our formulation?<\/strong><\/h2>\n\n\n\n

      The purpose is to show that liposomal encapsulated supplements can really make a difference to supplement absorption. With this human study, we wanted to prove that our product can overcome the problems associated with high-dose vitamin C absorption.<\/p>\n\n\n\n

      The Study<\/strong><\/h3>\n\n\n\n

      The bioavailability study described here was performed in association with our study partner, Surya Research Clinics, India.<\/p>\n\n\n\n

      What did we look at<\/strong><\/h3>\n\n\n\n

      We tested 40 healthy volunteers <\/strong>(20-50 years) divided randomly into four equally sized groups. This is an adequately sized group for pilot tests like ours. Here is a list of the formulations that each group were given:<\/p>\n\n\n\n